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KMID : 0377619700190050369
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Korean Jungang Medical Journal
1970 Volume.19 No. 5 p.369 ~ p.382
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Study on the Effect of Estriol in Cervical Tissue
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Abstract
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This paper is an article to study the effect of estriol in the cervix of rat, from chemical, histological and histochemical points of view.
The rats were grouped non-pregnant (ovariectomized) and pregnant with injection of progesterone, estradiol and estriol for 6 days 3mg daily, it daily and for daily respectively, and then Sodium, Potassium in cervical tissue were measured and histological, histochem cal findings examined. The results obtained from this study were, as follows:
1) Compared with effect of estradiol, estriol was increased weakly weight of uterine body, but fairy increased weight of uterine cervix.
2) Water content of cervical tissue in case of estriol injection was much more increased than estradiol and progesterone.
3) It is clarified that estriol increased Sodium in cervical tissue but Potassium was not changed significantly.
4) It was proved in every case that effect of estriol were produced remarkably an increase in edema, vascularity. vacuolization of basal epithelium and hypertrophy of cervical gland.
5) In histochemical staining, PAS positive substance, alkaline phosphatase, RNA and DNA were appeared much in the cervical tissue of rat who given estriol than that of progesterone, estradiol.
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